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In clinical practice, prolotherapy is widely used by regenerative medicine physicians and sports medicine specialists for shoulder instability , including: AC joint separation Rotator cuff tendinopathy Multidirectional instability Advantages of Prolotherapy Over Conventional Treatment Prolotherapy empowers the body to repair itself naturally, reducing the need for prolonged medications or surgical intervention

Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, and Faraci FM (2000)

Additionally, the composition of microbiota is highly flexible in response to diet and can undergo rapid and significant change [148]

Previous studies have demonstrated the cleavage of allylcarbamates 20 , propargyls 21,22 , or allenes 23